Turkish Journal of Oncology Turkish Society for Radiation Oncology
Article Open Access Volume 34 · 2019 pp. 016–022

Interventional Oncology: Should Interventional Radiotherapy (Brachytherapy) be Integrated into Modern Treatment Procedures?

György KOVÁCS1,2, Luca TAGLİAFERRİ3,4, Valentina LANCELLOTTA3,7, Attila KOVÁCS5, Roberto IEZZİ3,6,8, Maria-Antonetta GAMBACORTA3,7,9
1 Interdisciplinary Brachytherapy Unit, University of Lübeck/UKSH-CL, Lübeck-Germany
2 Gemelli-INTERACTS Educational Program Director, Rome-Italy
3 Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome-Italy
4 Gemelli-INTERACTS Course Teacher and Local Organizer, Rome-Italy
5 Department of Diagnostic and Interventional Radiology and Neuroradiology, Medi Clin Robert Janker Klinik, Bonn-Germany
6 Department of Radiological Sciences, Radiotherapy and Hematology, Institutodi Radiologia, Policlinico A. Gemelli, Rome-Italy
7 Gemelli-INTERACTS Courses Teacher, Rome-Italy
8 Università Cattolica del Sacro Cuore, Rome-Italy
Published: 2019 DOI: 10.5505/tjo.2019.4 Article ID: 1057
Abstract
OBJECTIVE

The delivery of a very high dose by radiotherapy to a dedicated target with minimal surrounding normal
tissue dose is a challenging situation. From a radiotherapy point of view, in several anatomic situations,
the most optimal method is the use of interventional radiotherapy (brachytherapy; IRT) alone or in
combination with other established interventional tumor cell eliminating methods.


METHODS

First, Interventional Radiotherapy, Interventional Radiology, Interventional Endoscopy and Interventional
Chemotherapy have the same aim of eliminating tumor tissue. Second, target definition and some
IRT application techniques need multidisciplinary teamwork.


RESULTS

Multidisciplinary teams have the best potential to offer the best possible cure in localized solid tumors or
in selected oligometastatic disease. Examples for this kind of service are given for H&N-, anal-, vaginal-,
breast-, prostate cancers as well as in oligometastatic disease. The combined use of interventional tumor
ablation techniques is demonstrated.


CONCLUSION

Interventional Oncology has the potential to improve the treatment results in localized solid cancers or
in selected oligometastatic disease, and large workload Interventional Oncology Centers could have an
important role in the patient service, in the education as well as in the clinical research.

Keywords: Brachytherapy; interventional oncology; interventional radiotherapy; multidisciplinarity; personalized medicine; world-class medicine

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