METHODS
In total 148 patients (50 females, 98 males; median age 60; range 24 to 90 years) (128 (86%) OC; 20 (14%) OP) were evaluated. Stage distribution is as follows; stage-I: 15 (10%); stage-II: 14 (9%); stage-III: 35 (24%); stage-IV: 84 (57%). Adjuvant radiotherapy performed in 67 (45%) patients; definitive radiotherapy in 81 (55%) patients. Twenty seven (18%) patients received concomittant boost radiotherapy and 23 (16%) received concomittant cisplatin. Median total dose was 70 Gy (35-78) in the definitive setting and 51 Gy (21-70) in the adjuvant setting.
RESULTS
Median follow-up was 25 (3-158) months. In patients receiving adjuvant radiotherapy, 2 and 5 years overall survival (OS) and disease free interval (DFI) rates were respectively; 75%; 61% and 75%; 64%. In definitive setting 2 and 5 years OS rates were 48%; 28% and DFI rates were 36%; 24% for OC; 2 and 5 years OS rates were 54%; 18% and DFI rates were 46%; 46% for OP cancer patients.
CONCLUSION
It is potentially possible to achive better results with combined treatment modalities in especially locally advanced OC and OP tumours.
Keywords: Head and neck cancer/mortality/radiotherapy; radiotherapy/ adverse effects/methods; oral cavity tumours; oropharynx tumours; survival rate
