METHODS
572 multiple primary tumors ( MPTs) (286 patients) out of 2 0.895 tumors recorded during the period of 1993-2005 by office of ICR located in IAEAH were analyzed. Double tumors (DTs) were analyzed. Chi-square test and Independent Samples t-test were performed by SPSS 10.0.
RESULTS
Of patients with MPTs 53.2% had synchronous whereas 43.1% had metachronous. The mean age were 55.81±15.4 years for ST group; 61.49±13.32 for DT group (p<0.001). Urogenital tumors (30.9%) and skin tumors (17.1%) in DTs group were higher than ST group statistically. The mean interval of DT was 44.4±30.82 (38.99-49.77) months.
CONCLUSION
Field cancerization, theory of a common clonal origin or screening effect may account for the relatively frequent association of urogenital tumors.
Keywords: Tumor; multiple primaries; single primary; cancer registry
