Turkish Journal of Oncology Turkish Society for Radiation Oncology
Article Open Access Volume 19 · Issue 3 · 2004 pp. 119–124

PIGMENTED VILLONODULAR SYNOVITIS AND RADIOTHERAPY, REPORT OF TWO CASES

Dr. Ayşe Nur DEMİRAL1, Dr. Evrim BAYMAN1, Dr. Hasan HAVITÇIOĞLU2, Dr. Metin MANİSALI3, Dr. Sermin ÖZKAL4, Dr. Mehmet ŞEN1, Dr. Münir KINAY1
1 Dokuz Eylül Üniversitesi Radyasyon Onkolojisi AD, İzmir
2 Dokuz Eylül Üniversitesi Ortopedi ve Travmatoloji AD, İzmir
3 Dokuz Eylül Üniversitesi Radyodiyagnostik AD, İzmir
4 Dokuz Eylül Üniversitesi Patoloji AD, İzmir
Published: 2004 Pubmed: 70226 Article ID: 643
Abstract
Pigmented villonodular synovitis (PVNS) (=Tenosynovial giant cell tumour) is a rare benign tumour originating from joints, tendon sheaths or bursa membranes. Although general treatment modality is surgery, postoperative local recurrence rate varies between %8 and %56. Radiotherapy is recommended in the cases who have a high recurrence risk.


In this report, the experience of postoperative radiotherapy has been presented in two cases with a diagnosis of PVNS.


The first case is a patient with diffuse PVNS of the knee who was referred for postoperative radiotherapy after her fourth local recurrence. The second one has a localized PVNS in the distal part of lower extremity. Clinical and radiologic features of the disease, as well as treatment results have been emphasized in the light of the presentation of these cases and experience from retrospective series. Postoperative radiotherapy is a preventive treatment approach in cases with a high risk of recurrence after excision. The use of postoperative radiotherapy makes it possible both to reduce the recurrence risk and to project the joint function.

Keywords: Pigmented Villonodular Synovitis, Tenosynovial giant cell tumour, radiotherapy

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