METHODS
The study included 61 TPC cases. In each case, the presence
of the lymphocyte infiltration in the tumor tissue and nonneoplastic
parenchyma was graded semi-quantitatively using a
scale of 0 to 3. The cases were classified in two groups, TPC including
CLT (Group I) and TPC not including CLT (Group II).
RESULTS
CLT was detected in 26.3% (Group I) of the TPCs and TIL
was observed in 77% of the Group I cases; no lymphoid infiltration
compatible with TIL was detected in Group II. A significant
difference was observed in the TIL density between
Groups I and II.
CONCLUSION
CLT is a frequent finding in TPC, and the presence of TIL is
related to CLT.
Keywords: Lymphocytic thyroiditis; papillary carcinoma; thyroid; tumor-infiltrating lymphocytes