Turkish Journal of Oncology Turkish Society for Radiation Oncology
Article Open Access Volume 25 · Issue 3 · 2010 pp. 087–092

Hematological parameters in lung cancer

Murat SERİLMEZ1
1 İstanbul Üniversitesi Onkoloji Enstitüsü, Temel Onkoloji Anabilim Dalı, Kanser Biyokimyası Bilim Dalı, İstanbul
2 İstanbul Üniversitesi Onkoloji Enstitüsü, Prevantif Onkoloji Anabilim Dalı, İstanbul
3 İstanbul Üniversitesi Onkoloji Enstitüsü, Klinik Onkoloji Anabilim Dalı, İstanbul
Published: 2010 Pubmed: 94951 Article ID: 753
Abstract
OBJECTIVES

Lung cancer is a disease of uncontrolled cell growth in tissues
of the lung. We aimed to analyze the blood count evaluation
in patients with lung cancer who received radiotherapy and/or
chemotherapy with respect to any changes in hematological
parameter levels.


METHODS

The study group consisted of 51 patients histologically confirmed
as having lung cancer. Blood samples were obtained on the first
admission before initial platinum-based chemotherapy (n=13)
and before platinum-based chemotherapy with simultaneously
applied radiotherapy (n=38); samples were obtained again six
weeks after chemotherapy was performed. The hematological
parameters of patients were determined by blood count analyzer.


RESULTS

There were statistical differences between the groups with respect
to white blood cells (WBC) (p<0.02), hemoglobin (Hb)
(p<0.002), and hematocrit (Hct) (p<0.03). There was no significant
difference between before and after chemotherapy and
chemotherapy-radiotherapy values (p>0.05).


CONCLUSION

We suggest that differences between WBC, Hb, and Hct values
may be attributed to patients having different histological
types.

Keywords: Lung cancer; hemogram; chemotherapy; radiotherapy

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