Turkish Journal of Oncology Turkish Society for Radiation Oncology
Article Open Access Volume 26 · Issue 3 · 2011 pp. 108–114

Evaluation of Hodgkin lymphoma cases and determination of prognostic factors

Mesut ŞEKER1
1 Tekirdağ Devlet Hastanesi, Tıbbi Onkoloji Kliniği, Tekirdağ
2 Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Tıbbi Onkoloji Kliniği, İstanbul
3 Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Radyasyon Onkolojisi Kliniği, İstanbul
Published: 2011 Pubmed: 105024 Article ID: 784
Abstract
OBJECTIVES

The aim of this study was to investigate the prognostic factors
affecting survival in patients with Hodgkin lymphoma.


METHODS

In this study, we reviewed retrospectively 165 patients with
Hodgkin lymphoma. A total of 165 patients were eligible, including
82 female and 83 male patients. The median follow-up
time was 34 (3-139) months.


RESULTS

Five-year overall survival (OS) and disease-free survival
rates for the entire group were 88.5% and 52%, respectively.
In univariate analysis, age (p<0.0001), stage (p<0.005),
Eastern Cooperative Oncology Group (ECOG) performance
status (p<0.0001), B symptoms (p=0.01), serum albumin levels
(p=0.01), and serum lactate dehydrogenase (LDH) levels
(p=0.04) significantly affected OS. Multivariate analysis
showed that only ECOG performance status was an important
prognostic factor for OS (p<0.001).


CONCLUSION

By increasing the number of patients, these results may contribute
to the information about demographical data and treatment
outcomes in patients with Hodgkin lymphoma in our country.

Keywords: Hodgkin lymphoma; prognostic factor

Article information

7,059 Views
2,734 Downloads
View / Download PDF

Current Issue Vol 26 · Iss 3

Submit manuscript
Most read & early access
Click an article to open abstract.
No early access articles.
View all articles