Bevacizumab is a monoclonal antibody exerting its effect
through binding vascular endothelial growth factor and is
used in addition to standard chemotherapy in patients with
metastatic colon cancer. Although it usually has tolerable side
effects, it is known to increase the risk of thromboembolism.
The presented case had severe headache during bevacizumab
therapy and according to the results of investigations, the patient
was diagnosed as cerebral venous thrombosis. Cerebral
venous thrombosis is a rare complication of this treatment and
should certainly be kept in mind in the differential diagnosis,
even in presence of normal neurological examination findings.
Keywords: Headache; bevacizumab; cerebral venous thrombosis
