Turkish Journal of Oncology Turkish Society for Radiation Oncology
Article Open Access Volume 28 · Issue 4 · 2013 pp. 179–186

Designing gene therapy vectors targeting tumor cell endothelium

Pınar ÖZKAL BAYDIN, Hakan AKBULUT
1 Ankara Üniversitesi Tıp Fakültesi, Tıbbi Onkoloji Bilimdalı, Ankara
Published: 2013 Article ID: 875
Abstract
Angiogenesis is essential for tumor growth and metastasis.
Targeting angiogenesis is one of the recent progresses in the
therapeutic area of cancer. Gene therapy is one of the promising
strategies in the treatment of cancer. The gene therapy
vectors targeting tumor endothelium carry the great therapeutic
potential in cancer.

Keywords: Gene therapy; intercellular adhesion molecule2; cancer; cytosine deaminase vascular endothel

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