METHODS
We investigated the serum MMP-9 and TIMP-1 values in 20 lung cancer patients by ELISA and the results were compared with the controls (n=20).
RESULTS
MMP-9 (p<0.001) and TIMP-1 (p<0.001) values of patients were significantly higher than the controls.
CONCLUSION
Our data indicate that detection of serum levels of MMP-9 and TIMP-1 can be used as diagnostic parameters for lung cancer.
Keywords: Gelatinase B; lung cancer; lung/metabolism/radiation e ffects; lung neoplasms/blood/enzymology /radiotherapy; Matrix Metalloproteinases; MMP 9; tissue inhibitor of Metalloproteinase- 1
