Turkish Journal of Oncology Turkish Society for Radiation Oncology
Article Open Access Volume 30 · Issue 1 · 2015 pp. 016–020

Clinical features of Hodgkin's lymphoma patients and retrospective analysis of treatment results: a single center experience

Yahyahan MEMİŞ, Mustafa KANDAZ, Lasif SERDAR, Özlem AYNACI, Aslı ŞAHBAZ, Gülşen SOYDEMİR, Zümrüt BAHAT, Emine CANYILMAZ, Adnan YÖNEY
1 Karadeniz Teknik Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, Trabzon
Published: 2015 Article ID: 905
Abstract
OBJECTIVES

Study clinical features and treatment results of patients with
Hodgkin's lymphoma and investigate prognostic factors affecting
survival.


METHODS

Data of 92 Hodgkin's lymphoma patients treated and monitored
at our center between 1996 and 2013 was studied retrospectively.


RESULTS

73% of the patients had early stage (stage I-II) and 27% of the
patients had late stage (stage III-IV) of the disease. The most
common histological types were nodular sclerosis Hodgkin's
lymphoma (47%) and mixed cellular Hodgkin's lymphoma
(MCHL) (35%). Median survival time was 193.08±15.41
months and 1-, 3-, 5- and 10-year survival rates were 97.7%,
87.1%, 80.4% and 72.9% respectively. In univariate analysis,
stage (p<0.0001), bulky disease (p<0.025), presence of risk
factors (p<0.0001) and recurrence (p<0.027) were found to be
variables with effects on overall survival.


CONCLUSION

Median survival time and survival rates of our study are compatible
with those of other studies in the literatüre.

Keywords: Stage; Hodgkin's lymphoma; survival; prognostic factors

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