THE RESULTS OBTAINED IN THE TREATMENT OF ADULT ALL CASES WITH COMBINED CHEMOTHERAPY

In this retrospective study, combined chemotherapy results of 53 adult patients diagnosed as acute lymphoblastic leukemia since 1973 were analysed. Remission was achieved at 34 patients (% 81) treated with Vincristine and prednisolone and at 8 patients (% 72.7) treated with vincristine, prednisolone and daunorubicin. The median remission duration was 122 days.Six months disease free survival was 33 percent. Patients older than thirty years old and with high leucocytosis had a low remission rate and a short remission duration. Meningeal involvement did not occur in any patient treated for central nervous system prophylaxis.