THE PRELIMINARY RESULTS OF RADIOTHERAPY IN EARLY STAGE (T1-T2) LARYNGEAL CANCER

In early stage larynx carcinoma, the function preserving treatment can be performed only if patients evaluated properly. In this study we present the preliminary results of 29 patients of early stage larynx carcinoma which were treated according to the prospective larynx carcinoma protocol of Dokuz Eylül Head and Neck Cancer Group. 28 patients were male and 1 patient was female. The average age was 61.5 (27-87). 6 patients were staged as Tis NO, 15 patients as T1NO and 8 patients as T2NO. In 25 cases, the tumor localization was in the glottic and 4 cases in the supraglottic area. The tumor histology was squamous cell carcinoma in 22 patients, in-situ carcinoma 6 and small cell carcinoma in 1 patient. Lung cancer was detected as a second primary in 1 patient. Diagnosis was made by biopsy in 20 cases, by stripping in 7 cases, by cordectomy in one case and by mass excision in one case. All cases were treated by radiotherapy alone. Treatment was completed in all cases. The delivered total dose was 66-70 Gy in 33-35 fractions. There was total tumor regression in all cases 2 months after radiotherapy. No serious side effects were observed. The voice quality was defined as "excellent" in 19 patients, 'good' in 9 patients. Only in the cordectomy case the voice quality was bad. The case with lung cancer is lost to follow up. Two cases died because of other reasons and the rest are disease free.