Medical treatment in childhood metastatic adrenocortical carcinoma: case report

Adrenocortical carcinoma is a rare endocrine tumor in childhood.
It is curable when it is resected totally. However, medical
therapy is challenging in patients with metastatic disease.
Herein, we present the response to various salvage chemotherapy
modalities in addition to mitotane therapy, which
were administered to a child with progressive and metastatic
adrenocortical tumor. The patient has been under follow-up
with progressive disease for 17 months.

Keywords: Adrenocortical carcinoma; hand-foot syndrome; gemcitabine; capecitabine; paclitaxel; sorafenib