Whole brain radiotherapy results of patients with brain metastases and investigation of their prognostic factors

METHODS

Whole brain radiotherapy results and prognostic factors of 62
patients with brain metastasis were studied retrospectively.

RESULTS

The median survival rate in our study was 6.9 months. Single
variation analysis demonstrated statistically significant survival
results independently in female patients, with Karnofsky
performance scale value of 70 and over, patients with controlled
primary disease, RPA class I, and diagnosed with breast
cancer (p<0.05). The results obtained from multi-variation
analysis demonstrated statistically significant survival results
among female patients, patients with an age of 65 years old
and below as well as patients with solitary metastasis and who
had undergone surgery (p<0.05).

CONCLUSION

Prognostic factors of patients must be considered in the treatment
of brain metastases by selecting the most suitable process
through radiosurgical, surgical resection, and/or whole
brain radiotherapy.

Keywords: Brain metastasis; prognostic factors; RPA; survival