Achantosis Nigricans (AN) is a skin disorder characterised
with hyperpigmented hyperkeratotic lesions. It occurs mostly
in association with insulin resistance while it may also
arise as a symptom of visceral malignancies. In the occurrence
of AN considered as associated with malignancy, a detailed
examination may be necessary to identify underlying
malignancy. 85% of malign AN cases abdominal adenocarcinomas,
and especially 60% of those are gastric adenocarcinomas.
A 44-year-old male patient applied to our clinic with
hyperpigmentation and hyperkeratosis, widespread body
pain and weight loss within 3-4 months. Skin symptoms
were reviewed as acanthosis nigricans. He had no endocrinological
diseases such as DM or obesity. Due to ocurrence
of many skin symptoms in accordance with acanthosis nigricans
in a rapid growth on our patient, no findings of other AN
causes, systemic symptoms such as the age of patient and
weight loss, it is considered as malign AN.
Keywords: Acanthosis nigricans
