Chemotherapy extravasation results in skin necrosis and cellulitis: a case report

Extravasation, the accidental leakage of an anticancer agent
from a vessel into the surrounding tissues, can lead to irreversible
local injuries and severe disability. Altough several
oral chemotherapy agents have been developed, most chemotherapy
agents are administered intravenously. The extravasation
of cancer chemotherapeutic agents can easily occur
and may cause severe and irreversible local injuries. The
incidence of extravasation of chemotherapeutic agents has
been reported to ocur in 0.01–6.9% of cases. Extravasated
drugs are classified according to their potential for causing
damage as vesicant, irritant and nonvesicant. In this report
we represent a multipl myeloma patient who has skin necrosis
and cellulitis after chemotherapy infusion.

Keywords: Extravasation; chemotherapy; necrosis