The increased glucose metabolism results increased 18FFluorodeoxyglucose
(FDG) accumulation of the malignant
cells. Similarly, Hodgkin's lymphoma (HL) show high FDG
uptake. Lymphocyte-predominant types of HL demonstrate
lower FDG accumulation than classic type HL. PET/CT can
detect almost all lesion greater than 0.5–1 cm. Additionally,
FDG PET/CT help us in monitoring treatment response by
showing glucose metabolism and FDG uptake of the cells after
chemotherapy. The sensitivity of FDG PET/CT is higher
than other imaging modalities in detecting nodular or diffuse
lesions of HL. Also, it has higher sensitivity in showing bone
marrow involvement than bone marrow biopsy. As a result,
FDG PET/CT is a widely accepted and superior imaging
modality in staging, re-staging and evaluating treatment response
of pediatric HL.
Keywords: FDG PET/CT, pediatric Hodgkin's lymphoma
