DUODENAL ADENOCARCINOMA WITH BONE METASTASIS, CASE REPORT

Small bowel adenocarcinoma is a relatively rare malignancy. Only limited information is available on the incidence, prognosis, and the role of chemotherapy and radiotherapy in the treatment of this disease. Duodenal adenocarcinoma accounts for more than 48% of all cases of small bowel adenocarcinoma. Resectability is the key prognostic factor, along with age, performance status, tumor location, and presence of distant metastasis. Although the activity of 5-FU-based regimens has been documented in case reports, the assessment of clinical benefit is hindered by the lack of prospective, randomized data.

Here, we present a rare case of duedonal adenocarcinoma with bone metastasis managed with surgery, postoperative chemotherapy and radiotherapy and related literature review.

Keywords: Small bowel adenocarcinoma, duedonal tumour, bone metastasis, chemotherapy, radiotherapy